Clinical Positions

Clinical Positions2017-12-05T09:13:13+00:00

Leading Experts Agree:

Blood Antibody Testing “Has No Current Role In The Management of H. pylori.”

When it comes to testing patients for H. pylori, are you making the choice the experts are
clearly recommending? In the past, the most often chosen test method for H. pylori was the
blood antibody test. Fast. Cheap. Easy. That doesn’t mean most effective. Today, clinical data
is clearly driving best practices to evolve. Consider the positions of just a few of the experts
setting today’s guidelines and reimbursement policies:

Leading Clinical Positions

ReimbursementBlood Antibody TestUrea Breath Test (UBT)
American College of Gastroenterology“A positive blood antibody test is no better than a coin toss for predicting active H. pylori infection.”“UBT is the most reliable non-endoscopic test to document eradication of H. pylori infection.”
Mayo Clinic Laboratories“Serologic testing for H. pyloriresults should be considered with significant caution.”“Adistinct advantage of [UBT] is that it can also be used to determine treatment efficacy.”
European Helicobacter Study Group“The blood antibody test has no current role in the management of H. pylori infection.”“The diagnostic accuracy of the UBT is >95% in studies. The UBT is an accurate, practical, and readily available test.”
Quest Diagnostics Laboratories“Serology-based methods cannot distinguish between active and resolved infection.These tests are not recommended for initial diagnosis of H. pylori infection or for confirming eradication. Thus, serology-based tests are not offered by Quest Diagnostics“These assays (UBT and stool antigen) have been recommended by the American College of Gastroenterologists (ACG) as the most accurate noninvasive tests for diagnosis of H. pylori infection and for confirmation of eradication after therapy